Advanced paternal age and reproductive outcome.
نویسندگان
چکیده
Women have been increasingly delaying the start of motherhood in recent decades. The same trend is seen also for men. The influence of maternal age on fertility, chromosomal anomalies, pregnancy complications, and impaired perinatal and post-natal outcome of offspring, has been thoroughly investigated, and these aspects are clinically applied during fertility and pregestational counseling. Male aging and reproductive outcome has gained relatively less attention. The purpose of this review is to evaluate updated and relevant literature on the effect of paternal age on reproductive outcome.
منابع مشابه
Paternal age and assisted reproductive technology outcome in ovum recipients.
This study suggests that paternal age may be inversely associated with reproductive outcome, as demonstrated by a decline in fertilization, blastocyst formation, implantation and cryopreservation rates with advancing age.
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BACKGROUND It is well known that miscarriage risk increases with age. However, studies usually investigate only maternal age effects. We investigated both maternal age and paternal age effects on miscarriage risk to provide insight into this frequent reproductive failure. METHODS The last planned pregnancies (n = 3174) that ended in a birth or miscarriage were analysed in a retrospective popu...
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Over the last decade, there has been a significant increase in average paternal age when the first child is conceived, either due to increased life expectancy, widespread use of contraception, late marriages and other factors. While the effect of maternal ageing on fertilization and reproduction is well known and several studies have shown that women over 35 years have a higher risk of infertil...
متن کاملP-155: Outcome of Assisted Reproductive Technology in Women Aged 40 Years and Older
Background: Human fertility has been declined all over the world. Advanced women’s age is one of the most important factors in determining the success of reproduction and ageing has negative impact on ART outcome and advanced female age decreases the chance of live birth rates achieved using ART, especially after 40 years of age. The purpose of this study was to evaluate ART outcomes regarding ...
متن کاملAdvancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice
Due to socioeconomic factors, more couples are choosing to delay conception than ever. Increasing average maternal and paternal age in developed countries over the past 40 years has raised the question of how aging affects reproductive success of males and females. Since oxidative stress in the male reproductive tract increases with age, we investigated the impact of advanced paternal age on th...
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ورودعنوان ژورنال:
- Asian journal of andrology
دوره 14 1 شماره
صفحات -
تاریخ انتشار 2012